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About us

About us

AATHEN High-level cluster research goal is defined in two points :

  • Identify new Angiotensin Receptor Blocker (ARB)-like small molecules with non-blood pressure-related therapeutic properties (cancer, cardiovascular, pulmonary, neurodegenerative, COVID-19, diabetes, etc). 

  • Generate new IP and spin-off companies, improve grant submission competitiveness and facilitate translational collaborations.

With the help of Mitacs and other partners, we have successfully designed and synthesized +30 novel ARB-derived small molecules that no longer block AT1R but have retained at least some of their therapeutic properties. Not only were invention disclosures filed with UILO but unique non-BP related therapeutic blood biomarkers were identified and a spin-off company created (ARbio Therapeutics), supporting the concept that significant technological developments can arise from existing ARBs.

 

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The UBC Advanced Angiotensin Therapeutic Network

#101-MBE, McGavin Building, 2386 East Mall
Vancouver, BC Canada V6T 123
E-mail angiotensin.thera@ubc.ca

Research Excellence Clusters at UBC Vancouver is a joint initiative of the Provost and Vice-President, Academic, UBC Vancouver and the Vice-President, Research and Innovation. Funding support for the clusters is provided by Academic Excellence Funds – UBC Vancouver.

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